Hiestrone
Brand names,
Hiestrone
Analogs
Hiestrone
Brand Names Mixture
- Cimicifuga Plex (Caulophyllum Thalictroides + Cimicifuga Racemosa + Copper + Cotton Plant + Estrone + Histamine Dihydrochloride + Hypothalamus + Magnesium Phosphate Dibasic + Pituitary Whole + Platinum + Sepia Officinalis L + Thyroid)
- Holis 98 (Dioscorea Vilosa + Estrone + Salvia + Saw Palmetto)
Hiestrone
Chemical_Formula
C18H22O2
Hiestrone
RX_link
No information avaliable
Hiestrone
fda sheet
Hiestrone
msds (material safety sheet)
Hiestrone
Synthesis Reference
G. Anner, K. Miescher, and Helv. Chem. Acta. 31, 2173(1948)
Hiestrone
Molecular Weight
270.366 g/mol
Hiestrone
Melting Point
254.5-256 oC
Hiestrone
H2O Solubility
3 g/100mL
Hiestrone
State
Solid
Hiestrone
LogP
4.067
Hiestrone
Dosage Forms
Vaginal cream; Vaginal suppository; Patch; Skin gel; Tablet; IM injectable suspension
Hiestrone
Indication
For management of Menopausal and postmenopausal disorders
Hiestrone
Pharmacology
Estrone, a synthetically prepared or naturally occurring steroidal estrogen obtained from pregnant equine urine, is the primary circulating estrogen after menopause. Estrone is naturally derived from the peripheral conversion of androstenedione by an aromatase enzyme found in adipose tissues and is converted to estradiol in peripheral tissues. Estropipate is piperazine-stabilized estrone sulfate. Estrone, and estropipate are used to treat abnormalities related to gonadotropin hormone dysfunction, vasomotor symptoms, atrophic vaginitis, and vulvar atrophy associated with menopause, and for the prevention of osteoporosis due to estrogen deficiency.
Hiestrone
Absorption
43%
Hiestrone
side effects and Toxicity
Symptoms of overdose include nausea and vomiting. Withdrawal bleeding may occur in females.
Hiestrone
Patient Information
Hiestrone
Organisms Affected
Humans and other mammals