Folikrin
Brand names,
Folikrin
Analogs
Folikrin
Brand Names Mixture
- Cimicifuga Plex (Caulophyllum Thalictroides + Cimicifuga Racemosa + Copper + Cotton Plant + Estrone + Histamine Dihydrochloride + Hypothalamus + Magnesium Phosphate Dibasic + Pituitary Whole + Platinum + Sepia Officinalis L + Thyroid)
- Holis 98 (Dioscorea Vilosa + Estrone + Salvia + Saw Palmetto)
Folikrin
Chemical_Formula
C18H22O2
Folikrin
RX_link
No information avaliable
Folikrin
fda sheet
Folikrin
msds (material safety sheet)
Folikrin
Synthesis Reference
G. Anner, K. Miescher, and Helv. Chem. Acta. 31, 2173(1948)
Folikrin
Molecular Weight
270.366 g/mol
Folikrin
Melting Point
254.5-256 oC
Folikrin
H2O Solubility
3 g/100mL
Folikrin
State
Solid
Folikrin
LogP
4.067
Folikrin
Dosage Forms
Vaginal cream; Vaginal suppository; Patch; Skin gel; Tablet; IM injectable suspension
Folikrin
Indication
For management of Menopausal and postmenopausal disorders
Folikrin
Pharmacology
Estrone, a synthetically prepared or naturally occurring steroidal estrogen obtained from pregnant equine urine, is the primary circulating estrogen after menopause. Estrone is naturally derived from the peripheral conversion of androstenedione by an aromatase enzyme found in adipose tissues and is converted to estradiol in peripheral tissues. Estropipate is piperazine-stabilized estrone sulfate. Estrone, and estropipate are used to treat abnormalities related to gonadotropin hormone dysfunction, vasomotor symptoms, atrophic vaginitis, and vulvar atrophy associated with menopause, and for the prevention of osteoporosis due to estrogen deficiency.
Folikrin
Absorption
43%
Folikrin
side effects and Toxicity
Symptoms of overdose include nausea and vomiting. Withdrawal bleeding may occur in females.
Folikrin
Patient Information
Folikrin
Organisms Affected
Humans and other mammals