Crinovaryl
Brand names,
Crinovaryl
Analogs
Crinovaryl
Brand Names Mixture
- Cimicifuga Plex (Caulophyllum Thalictroides + Cimicifuga Racemosa + Copper + Cotton Plant + Estrone + Histamine Dihydrochloride + Hypothalamus + Magnesium Phosphate Dibasic + Pituitary Whole + Platinum + Sepia Officinalis L + Thyroid)
- Holis 98 (Dioscorea Vilosa + Estrone + Salvia + Saw Palmetto)
Crinovaryl
Chemical_Formula
C18H22O2
Crinovaryl
RX_link
No information avaliable
Crinovaryl
fda sheet
Crinovaryl
msds (material safety sheet)
Crinovaryl
Synthesis Reference
G. Anner, K. Miescher, and Helv. Chem. Acta. 31, 2173(1948)
Crinovaryl
Molecular Weight
270.366 g/mol
Crinovaryl
Melting Point
254.5-256 oC
Crinovaryl
H2O Solubility
3 g/100mL
Crinovaryl
State
Solid
Crinovaryl
LogP
4.067
Crinovaryl
Dosage Forms
Vaginal cream; Vaginal suppository; Patch; Skin gel; Tablet; IM injectable suspension
Crinovaryl
Indication
For management of Menopausal and postmenopausal disorders
Crinovaryl
Pharmacology
Estrone, a synthetically prepared or naturally occurring steroidal estrogen obtained from pregnant equine urine, is the primary circulating estrogen after menopause. Estrone is naturally derived from the peripheral conversion of androstenedione by an aromatase enzyme found in adipose tissues and is converted to estradiol in peripheral tissues. Estropipate is piperazine-stabilized estrone sulfate. Estrone, and estropipate are used to treat abnormalities related to gonadotropin hormone dysfunction, vasomotor symptoms, atrophic vaginitis, and vulvar atrophy associated with menopause, and for the prevention of osteoporosis due to estrogen deficiency.
Crinovaryl
Absorption
43%
Crinovaryl
side effects and Toxicity
Symptoms of overdose include nausea and vomiting. Withdrawal bleeding may occur in females.
Crinovaryl
Patient Information
Crinovaryl
Organisms Affected
Humans and other mammals