Kestrone
Brand names,
Kestrone
Analogs
Kestrone
Brand Names Mixture
- Cimicifuga Plex (Caulophyllum Thalictroides + Cimicifuga Racemosa + Copper + Cotton Plant + Estrone + Histamine Dihydrochloride + Hypothalamus + Magnesium Phosphate Dibasic + Pituitary Whole + Platinum + Sepia Officinalis L + Thyroid)
- Holis 98 (Dioscorea Vilosa + Estrone + Salvia + Saw Palmetto)
Kestrone
Chemical_Formula
C18H22O2
Kestrone
RX_link
No information avaliable
Kestrone
fda sheet
Kestrone
msds (material safety sheet)
Kestrone
Synthesis Reference
G. Anner, K. Miescher, and Helv. Chem. Acta. 31, 2173(1948)
Kestrone
Molecular Weight
270.366 g/mol
Kestrone
Melting Point
254.5-256 oC
Kestrone
H2O Solubility
3 g/100mL
Kestrone
State
Solid
Kestrone
LogP
4.067
Kestrone
Dosage Forms
Vaginal cream; Vaginal suppository; Patch; Skin gel; Tablet; IM injectable suspension
Kestrone
Indication
For management of Menopausal and postmenopausal disorders
Kestrone
Pharmacology
Estrone, a synthetically prepared or naturally occurring steroidal estrogen obtained from pregnant equine urine, is the primary circulating estrogen after menopause. Estrone is naturally derived from the peripheral conversion of androstenedione by an aromatase enzyme found in adipose tissues and is converted to estradiol in peripheral tissues. Estropipate is piperazine-stabilized estrone sulfate. Estrone, and estropipate are used to treat abnormalities related to gonadotropin hormone dysfunction, vasomotor symptoms, atrophic vaginitis, and vulvar atrophy associated with menopause, and for the prevention of osteoporosis due to estrogen deficiency.
Kestrone
Absorption
43%
Kestrone
side effects and Toxicity
Symptoms of overdose include nausea and vomiting. Withdrawal bleeding may occur in females.
Kestrone
Patient Information
Kestrone
Organisms Affected
Humans and other mammals