Ketohydroxy-Estratriene
Brand names,
Ketohydroxy-Estratriene
Analogs
Ketohydroxy-Estratriene
Brand Names Mixture
- Cimicifuga Plex (Caulophyllum Thalictroides + Cimicifuga Racemosa + Copper + Cotton Plant + Estrone + Histamine Dihydrochloride + Hypothalamus + Magnesium Phosphate Dibasic + Pituitary Whole + Platinum + Sepia Officinalis L + Thyroid)
- Holis 98 (Dioscorea Vilosa + Estrone + Salvia + Saw Palmetto)
Ketohydroxy-Estratriene
Chemical_Formula
C18H22O2
Ketohydroxy-Estratriene
RX_link
No information avaliable
Ketohydroxy-Estratriene
fda sheet
Ketohydroxy-Estratriene
msds (material safety sheet)
Ketohydroxy-Estratriene
Synthesis Reference
G. Anner, K. Miescher, and Helv. Chem. Acta. 31, 2173(1948)
Ketohydroxy-Estratriene
Molecular Weight
270.366 g/mol
Ketohydroxy-Estratriene
Melting Point
254.5-256 oC
Ketohydroxy-Estratriene
H2O Solubility
3 g/100mL
Ketohydroxy-Estratriene
State
Solid
Ketohydroxy-Estratriene
LogP
4.067
Ketohydroxy-Estratriene
Dosage Forms
Vaginal cream; Vaginal suppository; Patch; Skin gel; Tablet; IM injectable suspension
Ketohydroxy-Estratriene
Indication
For management of Menopausal and postmenopausal disorders
Ketohydroxy-Estratriene
Pharmacology
Estrone, a synthetically prepared or naturally occurring steroidal estrogen obtained from pregnant equine urine, is the primary circulating estrogen after menopause. Estrone is naturally derived from the peripheral conversion of androstenedione by an aromatase enzyme found in adipose tissues and is converted to estradiol in peripheral tissues. Estropipate is piperazine-stabilized estrone sulfate. Estrone, and estropipate are used to treat abnormalities related to gonadotropin hormone dysfunction, vasomotor symptoms, atrophic vaginitis, and vulvar atrophy associated with menopause, and for the prevention of osteoporosis due to estrogen deficiency.
Ketohydroxy-Estratriene
Absorption
43%
Ketohydroxy-Estratriene
side effects and Toxicity
Symptoms of overdose include nausea and vomiting. Withdrawal bleeding may occur in females.
Ketohydroxy-Estratriene
Patient Information
Ketohydroxy-Estratriene
Organisms Affected
Humans and other mammals