Ketophydroxyestrin
Brand names,
Ketophydroxyestrin
Analogs
Ketophydroxyestrin
Brand Names Mixture
- Cimicifuga Plex (Caulophyllum Thalictroides + Cimicifuga Racemosa + Copper + Cotton Plant + Estrone + Histamine Dihydrochloride + Hypothalamus + Magnesium Phosphate Dibasic + Pituitary Whole + Platinum + Sepia Officinalis L + Thyroid)
- Holis 98 (Dioscorea Vilosa + Estrone + Salvia + Saw Palmetto)
Ketophydroxyestrin
Chemical_Formula
C18H22O2
Ketophydroxyestrin
RX_link
No information avaliable
Ketophydroxyestrin
fda sheet
Ketophydroxyestrin
msds (material safety sheet)
Ketophydroxyestrin
Synthesis Reference
G. Anner, K. Miescher, and Helv. Chem. Acta. 31, 2173(1948)
Ketophydroxyestrin
Molecular Weight
270.366 g/mol
Ketophydroxyestrin
Melting Point
254.5-256 oC
Ketophydroxyestrin
H2O Solubility
3 g/100mL
Ketophydroxyestrin
State
Solid
Ketophydroxyestrin
LogP
4.067
Ketophydroxyestrin
Dosage Forms
Vaginal cream; Vaginal suppository; Patch; Skin gel; Tablet; IM injectable suspension
Ketophydroxyestrin
Indication
For management of Menopausal and postmenopausal disorders
Ketophydroxyestrin
Pharmacology
Estrone, a synthetically prepared or naturally occurring steroidal estrogen obtained from pregnant equine urine, is the primary circulating estrogen after menopause. Estrone is naturally derived from the peripheral conversion of androstenedione by an aromatase enzyme found in adipose tissues and is converted to estradiol in peripheral tissues. Estropipate is piperazine-stabilized estrone sulfate. Estrone, and estropipate are used to treat abnormalities related to gonadotropin hormone dysfunction, vasomotor symptoms, atrophic vaginitis, and vulvar atrophy associated with menopause, and for the prevention of osteoporosis due to estrogen deficiency.
Ketophydroxyestrin
Absorption
43%
Ketophydroxyestrin
side effects and Toxicity
Symptoms of overdose include nausea and vomiting. Withdrawal bleeding may occur in females.
Ketophydroxyestrin
Patient Information
Ketophydroxyestrin
Organisms Affected
Humans and other mammals