Estrona
Brand names,
Estrona
Analogs
Estrona
Brand Names Mixture
- Cimicifuga Plex (Caulophyllum Thalictroides + Cimicifuga Racemosa + Copper + Cotton Plant + Estrone + Histamine Dihydrochloride + Hypothalamus + Magnesium Phosphate Dibasic + Pituitary Whole + Platinum + Sepia Officinalis L + Thyroid)
- Holis 98 (Dioscorea Vilosa + Estrone + Salvia + Saw Palmetto)
Estrona
Chemical_Formula
C18H22O2
Estrona
RX_link
No information avaliable
Estrona
fda sheet
Estrona
msds (material safety sheet)
Estrona
Synthesis Reference
G. Anner, K. Miescher, and Helv. Chem. Acta. 31, 2173(1948)
Estrona
Molecular Weight
270.366 g/mol
Estrona
Melting Point
254.5-256 oC
Estrona
H2O Solubility
3 g/100mL
Estrona
State
Solid
Estrona
LogP
4.067
Estrona
Dosage Forms
Vaginal cream; Vaginal suppository; Patch; Skin gel; Tablet; IM injectable suspension
Estrona
Indication
For management of Menopausal and postmenopausal disorders
Estrona
Pharmacology
Estrone, a synthetically prepared or naturally occurring steroidal estrogen obtained from pregnant equine urine, is the primary circulating estrogen after menopause. Estrone is naturally derived from the peripheral conversion of androstenedione by an aromatase enzyme found in adipose tissues and is converted to estradiol in peripheral tissues. Estropipate is piperazine-stabilized estrone sulfate. Estrone, and estropipate are used to treat abnormalities related to gonadotropin hormone dysfunction, vasomotor symptoms, atrophic vaginitis, and vulvar atrophy associated with menopause, and for the prevention of osteoporosis due to estrogen deficiency.
Estrona
Absorption
43%
Estrona
side effects and Toxicity
Symptoms of overdose include nausea and vomiting. Withdrawal bleeding may occur in females.
Estrona
Patient Information
Estrona
Organisms Affected
Humans and other mammals