Cristallovar
Brand names,
Cristallovar
Analogs
Cristallovar
Brand Names Mixture
- Cimicifuga Plex (Caulophyllum Thalictroides + Cimicifuga Racemosa + Copper + Cotton Plant + Estrone + Histamine Dihydrochloride + Hypothalamus + Magnesium Phosphate Dibasic + Pituitary Whole + Platinum + Sepia Officinalis L + Thyroid)
- Holis 98 (Dioscorea Vilosa + Estrone + Salvia + Saw Palmetto)
Cristallovar
Chemical_Formula
C18H22O2
Cristallovar
RX_link
No information avaliable
Cristallovar
fda sheet
Cristallovar
msds (material safety sheet)
Cristallovar
Synthesis Reference
G. Anner, K. Miescher, and Helv. Chem. Acta. 31, 2173(1948)
Cristallovar
Molecular Weight
270.366 g/mol
Cristallovar
Melting Point
254.5-256 oC
Cristallovar
H2O Solubility
3 g/100mL
Cristallovar
State
Solid
Cristallovar
LogP
4.067
Cristallovar
Dosage Forms
Vaginal cream; Vaginal suppository; Patch; Skin gel; Tablet; IM injectable suspension
Cristallovar
Indication
For management of Menopausal and postmenopausal disorders
Cristallovar
Pharmacology
Estrone, a synthetically prepared or naturally occurring steroidal estrogen obtained from pregnant equine urine, is the primary circulating estrogen after menopause. Estrone is naturally derived from the peripheral conversion of androstenedione by an aromatase enzyme found in adipose tissues and is converted to estradiol in peripheral tissues. Estropipate is piperazine-stabilized estrone sulfate. Estrone, and estropipate are used to treat abnormalities related to gonadotropin hormone dysfunction, vasomotor symptoms, atrophic vaginitis, and vulvar atrophy associated with menopause, and for the prevention of osteoporosis due to estrogen deficiency.
Cristallovar
Absorption
43%
Cristallovar
side effects and Toxicity
Symptoms of overdose include nausea and vomiting. Withdrawal bleeding may occur in females.
Cristallovar
Patient Information
Cristallovar
Organisms Affected
Humans and other mammals