Thelestrin
Brand names,
Thelestrin
Analogs
Thelestrin
Brand Names Mixture
- Cimicifuga Plex (Caulophyllum Thalictroides + Cimicifuga Racemosa + Copper + Cotton Plant + Estrone + Histamine Dihydrochloride + Hypothalamus + Magnesium Phosphate Dibasic + Pituitary Whole + Platinum + Sepia Officinalis L + Thyroid)
- Holis 98 (Dioscorea Vilosa + Estrone + Salvia + Saw Palmetto)
Thelestrin
Chemical_Formula
C18H22O2
Thelestrin
RX_link
No information avaliable
Thelestrin
fda sheet
Thelestrin
msds (material safety sheet)
Thelestrin
Synthesis Reference
G. Anner, K. Miescher, and Helv. Chem. Acta. 31, 2173(1948)
Thelestrin
Molecular Weight
270.366 g/mol
Thelestrin
Melting Point
254.5-256 oC
Thelestrin
H2O Solubility
3 g/100mL
Thelestrin
State
Solid
Thelestrin
LogP
4.067
Thelestrin
Dosage Forms
Vaginal cream; Vaginal suppository; Patch; Skin gel; Tablet; IM injectable suspension
Thelestrin
Indication
For management of Menopausal and postmenopausal disorders
Thelestrin
Pharmacology
Estrone, a synthetically prepared or naturally occurring steroidal estrogen obtained from pregnant equine urine, is the primary circulating estrogen after menopause. Estrone is naturally derived from the peripheral conversion of androstenedione by an aromatase enzyme found in adipose tissues and is converted to estradiol in peripheral tissues. Estropipate is piperazine-stabilized estrone sulfate. Estrone, and estropipate are used to treat abnormalities related to gonadotropin hormone dysfunction, vasomotor symptoms, atrophic vaginitis, and vulvar atrophy associated with menopause, and for the prevention of osteoporosis due to estrogen deficiency.
Thelestrin
Absorption
43%
Thelestrin
side effects and Toxicity
Symptoms of overdose include nausea and vomiting. Withdrawal bleeding may occur in females.
Thelestrin
Patient Information
Thelestrin
Organisms Affected
Humans and other mammals