Esterone
Brand names,
Esterone
Analogs
Esterone
Brand Names Mixture
- Cimicifuga Plex (Caulophyllum Thalictroides + Cimicifuga Racemosa + Copper + Cotton Plant + Estrone + Histamine Dihydrochloride + Hypothalamus + Magnesium Phosphate Dibasic + Pituitary Whole + Platinum + Sepia Officinalis L + Thyroid)
- Holis 98 (Dioscorea Vilosa + Estrone + Salvia + Saw Palmetto)
Esterone
Chemical_Formula
C18H22O2
Esterone
RX_link
No information avaliable
Esterone
fda sheet
Esterone
msds (material safety sheet)
Esterone
Synthesis Reference
G. Anner, K. Miescher, and Helv. Chem. Acta. 31, 2173(1948)
Esterone
Molecular Weight
270.366 g/mol
Esterone
Melting Point
254.5-256 oC
Esterone
H2O Solubility
3 g/100mL
Esterone
State
Solid
Esterone
LogP
4.067
Esterone
Dosage Forms
Vaginal cream; Vaginal suppository; Patch; Skin gel; Tablet; IM injectable suspension
Esterone
Indication
For management of Menopausal and postmenopausal disorders
Esterone
Pharmacology
Estrone, a synthetically prepared or naturally occurring steroidal estrogen obtained from pregnant equine urine, is the primary circulating estrogen after menopause. Estrone is naturally derived from the peripheral conversion of androstenedione by an aromatase enzyme found in adipose tissues and is converted to estradiol in peripheral tissues. Estropipate is piperazine-stabilized estrone sulfate. Estrone, and estropipate are used to treat abnormalities related to gonadotropin hormone dysfunction, vasomotor symptoms, atrophic vaginitis, and vulvar atrophy associated with menopause, and for the prevention of osteoporosis due to estrogen deficiency.
Esterone
Absorption
43%
Esterone
side effects and Toxicity
Symptoms of overdose include nausea and vomiting. Withdrawal bleeding may occur in females.
Esterone
Patient Information
Esterone
Organisms Affected
Humans and other mammals