Kolpon
Brand names,
Kolpon
Analogs
Kolpon
Brand Names Mixture
- Cimicifuga Plex (Caulophyllum Thalictroides + Cimicifuga Racemosa + Copper + Cotton Plant + Estrone + Histamine Dihydrochloride + Hypothalamus + Magnesium Phosphate Dibasic + Pituitary Whole + Platinum + Sepia Officinalis L + Thyroid)
- Holis 98 (Dioscorea Vilosa + Estrone + Salvia + Saw Palmetto)
Kolpon
Chemical_Formula
C18H22O2
Kolpon
RX_link
No information avaliable
Kolpon
fda sheet
Kolpon
msds (material safety sheet)
Kolpon
Synthesis Reference
G. Anner, K. Miescher, and Helv. Chem. Acta. 31, 2173(1948)
Kolpon
Molecular Weight
270.366 g/mol
Kolpon
Melting Point
254.5-256 oC
Kolpon
H2O Solubility
3 g/100mL
Kolpon
State
Solid
Kolpon
LogP
4.067
Kolpon
Dosage Forms
Vaginal cream; Vaginal suppository; Patch; Skin gel; Tablet; IM injectable suspension
Kolpon
Indication
For management of Menopausal and postmenopausal disorders
Kolpon
Pharmacology
Estrone, a synthetically prepared or naturally occurring steroidal estrogen obtained from pregnant equine urine, is the primary circulating estrogen after menopause. Estrone is naturally derived from the peripheral conversion of androstenedione by an aromatase enzyme found in adipose tissues and is converted to estradiol in peripheral tissues. Estropipate is piperazine-stabilized estrone sulfate. Estrone, and estropipate are used to treat abnormalities related to gonadotropin hormone dysfunction, vasomotor symptoms, atrophic vaginitis, and vulvar atrophy associated with menopause, and for the prevention of osteoporosis due to estrogen deficiency.
Kolpon
Absorption
43%
Kolpon
side effects and Toxicity
Symptoms of overdose include nausea and vomiting. Withdrawal bleeding may occur in females.
Kolpon
Patient Information
Kolpon
Organisms Affected
Humans and other mammals