Folliculine
Brand names,
Folliculine
Analogs
Folliculine
Brand Names Mixture
- Cimicifuga Plex (Caulophyllum Thalictroides + Cimicifuga Racemosa + Copper + Cotton Plant + Estrone + Histamine Dihydrochloride + Hypothalamus + Magnesium Phosphate Dibasic + Pituitary Whole + Platinum + Sepia Officinalis L + Thyroid)
- Holis 98 (Dioscorea Vilosa + Estrone + Salvia + Saw Palmetto)
Folliculine
Chemical_Formula
C18H22O2
Folliculine
RX_link
No information avaliable
Folliculine
fda sheet
Folliculine
msds (material safety sheet)
Folliculine
Synthesis Reference
G. Anner, K. Miescher, and Helv. Chem. Acta. 31, 2173(1948)
Folliculine
Molecular Weight
270.366 g/mol
Folliculine
Melting Point
254.5-256 oC
Folliculine
H2O Solubility
3 g/100mL
Folliculine
State
Solid
Folliculine
LogP
4.067
Folliculine
Dosage Forms
Vaginal cream; Vaginal suppository; Patch; Skin gel; Tablet; IM injectable suspension
Folliculine
Indication
For management of Menopausal and postmenopausal disorders
Folliculine
Pharmacology
Estrone, a synthetically prepared or naturally occurring steroidal estrogen obtained from pregnant equine urine, is the primary circulating estrogen after menopause. Estrone is naturally derived from the peripheral conversion of androstenedione by an aromatase enzyme found in adipose tissues and is converted to estradiol in peripheral tissues. Estropipate is piperazine-stabilized estrone sulfate. Estrone, and estropipate are used to treat abnormalities related to gonadotropin hormone dysfunction, vasomotor symptoms, atrophic vaginitis, and vulvar atrophy associated with menopause, and for the prevention of osteoporosis due to estrogen deficiency.
Folliculine
Absorption
43%
Folliculine
side effects and Toxicity
Symptoms of overdose include nausea and vomiting. Withdrawal bleeding may occur in females.
Folliculine
Patient Information
Folliculine
Organisms Affected
Humans and other mammals