Mestronaq
Brand names,
Mestronaq
Analogs
Mestronaq
Brand Names Mixture
- Cimicifuga Plex (Caulophyllum Thalictroides + Cimicifuga Racemosa + Copper + Cotton Plant + Estrone + Histamine Dihydrochloride + Hypothalamus + Magnesium Phosphate Dibasic + Pituitary Whole + Platinum + Sepia Officinalis L + Thyroid)
- Holis 98 (Dioscorea Vilosa + Estrone + Salvia + Saw Palmetto)
Mestronaq
Chemical_Formula
C18H22O2
Mestronaq
RX_link
No information avaliable
Mestronaq
fda sheet
Mestronaq
msds (material safety sheet)
Mestronaq
Synthesis Reference
G. Anner, K. Miescher, and Helv. Chem. Acta. 31, 2173(1948)
Mestronaq
Molecular Weight
270.366 g/mol
Mestronaq
Melting Point
254.5-256 oC
Mestronaq
H2O Solubility
3 g/100mL
Mestronaq
State
Solid
Mestronaq
LogP
4.067
Mestronaq
Dosage Forms
Vaginal cream; Vaginal suppository; Patch; Skin gel; Tablet; IM injectable suspension
Mestronaq
Indication
For management of Menopausal and postmenopausal disorders
Mestronaq
Pharmacology
Estrone, a synthetically prepared or naturally occurring steroidal estrogen obtained from pregnant equine urine, is the primary circulating estrogen after menopause. Estrone is naturally derived from the peripheral conversion of androstenedione by an aromatase enzyme found in adipose tissues and is converted to estradiol in peripheral tissues. Estropipate is piperazine-stabilized estrone sulfate. Estrone, and estropipate are used to treat abnormalities related to gonadotropin hormone dysfunction, vasomotor symptoms, atrophic vaginitis, and vulvar atrophy associated with menopause, and for the prevention of osteoporosis due to estrogen deficiency.
Mestronaq
Absorption
43%
Mestronaq
side effects and Toxicity
Symptoms of overdose include nausea and vomiting. Withdrawal bleeding may occur in females.
Mestronaq
Patient Information
Mestronaq
Organisms Affected
Humans and other mammals