Femestrone Injection
Brand names,
Femestrone Injection
Analogs
Femestrone Injection
Brand Names Mixture
- Cimicifuga Plex (Caulophyllum Thalictroides + Cimicifuga Racemosa + Copper + Cotton Plant + Estrone + Histamine Dihydrochloride + Hypothalamus + Magnesium Phosphate Dibasic + Pituitary Whole + Platinum + Sepia Officinalis L + Thyroid)
- Holis 98 (Dioscorea Vilosa + Estrone + Salvia + Saw Palmetto)
Femestrone Injection
Chemical_Formula
C18H22O2
Femestrone Injection
RX_link
No information avaliable
Femestrone Injection
fda sheet
Femestrone Injection
msds (material safety sheet)
Femestrone Injection
Synthesis Reference
G. Anner, K. Miescher, and Helv. Chem. Acta. 31, 2173(1948)
Femestrone Injection
Molecular Weight
270.366 g/mol
Femestrone Injection
Melting Point
254.5-256 oC
Femestrone Injection
H2O Solubility
3 g/100mL
Femestrone Injection
State
Solid
Femestrone Injection
LogP
4.067
Femestrone Injection
Dosage Forms
Vaginal cream; Vaginal suppository; Patch; Skin gel; Tablet; IM injectable suspension
Femestrone Injection
Indication
For management of Menopausal and postmenopausal disorders
Femestrone Injection
Pharmacology
Estrone, a synthetically prepared or naturally occurring steroidal estrogen obtained from pregnant equine urine, is the primary circulating estrogen after menopause. Estrone is naturally derived from the peripheral conversion of androstenedione by an aromatase enzyme found in adipose tissues and is converted to estradiol in peripheral tissues. Estropipate is piperazine-stabilized estrone sulfate. Estrone, and estropipate are used to treat abnormalities related to gonadotropin hormone dysfunction, vasomotor symptoms, atrophic vaginitis, and vulvar atrophy associated with menopause, and for the prevention of osteoporosis due to estrogen deficiency.
Femestrone Injection
Absorption
43%
Femestrone Injection
side effects and Toxicity
Symptoms of overdose include nausea and vomiting. Withdrawal bleeding may occur in females.
Femestrone Injection
Patient Information
Femestrone Injection
Organisms Affected
Humans and other mammals