Oestrin
Brand names,
Oestrin
Analogs
Oestrin
Brand Names Mixture
- Cimicifuga Plex (Caulophyllum Thalictroides + Cimicifuga Racemosa + Copper + Cotton Plant + Estrone + Histamine Dihydrochloride + Hypothalamus + Magnesium Phosphate Dibasic + Pituitary Whole + Platinum + Sepia Officinalis L + Thyroid)
- Holis 98 (Dioscorea Vilosa + Estrone + Salvia + Saw Palmetto)
Oestrin
Chemical_Formula
C18H22O2
Oestrin
RX_link
No information avaliable
Oestrin
fda sheet
Oestrin
msds (material safety sheet)
Oestrin
Synthesis Reference
G. Anner, K. Miescher, and Helv. Chem. Acta. 31, 2173(1948)
Oestrin
Molecular Weight
270.366 g/mol
Oestrin
Melting Point
254.5-256 oC
Oestrin
H2O Solubility
3 g/100mL
Oestrin
State
Solid
Oestrin
LogP
4.067
Oestrin
Dosage Forms
Vaginal cream; Vaginal suppository; Patch; Skin gel; Tablet; IM injectable suspension
Oestrin
Indication
For management of Menopausal and postmenopausal disorders
Oestrin
Pharmacology
Estrone, a synthetically prepared or naturally occurring steroidal estrogen obtained from pregnant equine urine, is the primary circulating estrogen after menopause. Estrone is naturally derived from the peripheral conversion of androstenedione by an aromatase enzyme found in adipose tissues and is converted to estradiol in peripheral tissues. Estropipate is piperazine-stabilized estrone sulfate. Estrone, and estropipate are used to treat abnormalities related to gonadotropin hormone dysfunction, vasomotor symptoms, atrophic vaginitis, and vulvar atrophy associated with menopause, and for the prevention of osteoporosis due to estrogen deficiency.
Oestrin
Absorption
43%
Oestrin
side effects and Toxicity
Symptoms of overdose include nausea and vomiting. Withdrawal bleeding may occur in females.
Oestrin
Patient Information
Oestrin
Organisms Affected
Humans and other mammals