Femestrone Inj.
Brand names,
Femestrone Inj.
Analogs
Femestrone Inj.
Brand Names Mixture
- Cimicifuga Plex (Caulophyllum Thalictroides + Cimicifuga Racemosa + Copper + Cotton Plant + Estrone + Histamine Dihydrochloride + Hypothalamus + Magnesium Phosphate Dibasic + Pituitary Whole + Platinum + Sepia Officinalis L + Thyroid)
- Holis 98 (Dioscorea Vilosa + Estrone + Salvia + Saw Palmetto)
Femestrone Inj.
Chemical_Formula
C18H22O2
Femestrone Inj.
RX_link
No information avaliable
Femestrone Inj.
fda sheet
Femestrone Inj.
msds (material safety sheet)
Femestrone Inj.
Synthesis Reference
G. Anner, K. Miescher, and Helv. Chem. Acta. 31, 2173(1948)
Femestrone Inj.
Molecular Weight
270.366 g/mol
Femestrone Inj.
Melting Point
254.5-256 oC
Femestrone Inj.
H2O Solubility
3 g/100mL
Femestrone Inj.
State
Solid
Femestrone Inj.
LogP
4.067
Femestrone Inj.
Dosage Forms
Vaginal cream; Vaginal suppository; Patch; Skin gel; Tablet; IM injectable suspension
Femestrone Inj.
Indication
For management of Menopausal and postmenopausal disorders
Femestrone Inj.
Pharmacology
Estrone, a synthetically prepared or naturally occurring steroidal estrogen obtained from pregnant equine urine, is the primary circulating estrogen after menopause. Estrone is naturally derived from the peripheral conversion of androstenedione by an aromatase enzyme found in adipose tissues and is converted to estradiol in peripheral tissues. Estropipate is piperazine-stabilized estrone sulfate. Estrone, and estropipate are used to treat abnormalities related to gonadotropin hormone dysfunction, vasomotor symptoms, atrophic vaginitis, and vulvar atrophy associated with menopause, and for the prevention of osteoporosis due to estrogen deficiency.
Femestrone Inj.
Absorption
43%
Femestrone Inj.
side effects and Toxicity
Symptoms of overdose include nausea and vomiting. Withdrawal bleeding may occur in females.
Femestrone Inj.
Patient Information
Femestrone Inj.
Organisms Affected
Humans and other mammals