GSS 33
Brand names,
GSS 33
Analogs
GSS 33
Brand Names Mixture
- Cimicifuga Plex (Caulophyllum Thalictroides + Cimicifuga Racemosa + Copper + Cotton Plant + Estrone + Histamine Dihydrochloride + Hypothalamus + Magnesium Phosphate Dibasic + Pituitary Whole + Platinum + Sepia Officinalis L + Thyroid)
- Holis 98 (Dioscorea Vilosa + Estrone + Salvia + Saw Palmetto)
GSS 33
Chemical_Formula
C18H22O2
GSS 33
RX_link
No information avaliable
GSS 33
fda sheet
GSS 33
msds (material safety sheet)
GSS 33
Synthesis Reference
G. Anner, K. Miescher, and Helv. Chem. Acta. 31, 2173(1948)
GSS 33
Molecular Weight
270.366 g/mol
GSS 33
Melting Point
254.5-256 oC
GSS 33
H2O Solubility
3 g/100mL
GSS 33
State
Solid
GSS 33
LogP
4.067
GSS 33
Dosage Forms
Vaginal cream; Vaginal suppository; Patch; Skin gel; Tablet; IM injectable suspension
GSS 33
Indication
For management of Menopausal and postmenopausal disorders
GSS 33
Pharmacology
Estrone, a synthetically prepared or naturally occurring steroidal estrogen obtained from pregnant equine urine, is the primary circulating estrogen after menopause. Estrone is naturally derived from the peripheral conversion of androstenedione by an aromatase enzyme found in adipose tissues and is converted to estradiol in peripheral tissues. Estropipate is piperazine-stabilized estrone sulfate. Estrone, and estropipate are used to treat abnormalities related to gonadotropin hormone dysfunction, vasomotor symptoms, atrophic vaginitis, and vulvar atrophy associated with menopause, and for the prevention of osteoporosis due to estrogen deficiency.
GSS 33
Absorption
43%
GSS 33
side effects and Toxicity
Symptoms of overdose include nausea and vomiting. Withdrawal bleeding may occur in females.
GSS 33
Patient Information
GSS 33
Organisms Affected
Humans and other mammals