Oestrone en es it fr

Oestrone Brand names, Oestrone Analogs

Oestrone Brand Names Mixture

  • Prempro (conjugated estrogens + medroxyprogesteron)

Oestrone Chemical_Formula


Oestrone RX_link


Oestrone fda sheet

Oestrone FDA

Oestrone msds (material safety sheet)

Oestrone MSDS

Oestrone Synthesis Reference

Bates, Cohen, U.S. Pat. 2,565,115 (1951)

Oestrone Molecular Weight

372.412 g/mol

Oestrone Melting Point

173 oC

Oestrone H2O Solubility

0.0036 mg/ml

Oestrone State


Oestrone LogP

No information avaliable

Oestrone Dosage Forms

Tablet; Injection; Vaginal cream; Topical gel

Oestrone Indication

For the treatment of moderate to severe vasomotor symptoms associated with the menopause, atrophic vaginitis, osteoporosis, hypoestrogenism due to hypogonadism, castration, primary ovarian failure, breast cancer (for palliation only), and Advanced androgen-dependent carcinoma of the prostate (for palliation only)

Oestrone Pharmacology

Conjugated estrogens, a mixture of the water soluble salts of sulfate esters from estrone, equilin, 17 α-dihydroequilin, and other related steroids, may be derived from pregnant equine urine or yam and soy plants. Estrogens are important in the development and maintenance of the female reproductive system and secondary sex characteristics. They promote growth and development of the vagina, uterus, and fallopian tubes, and enlargement of the breasts. Indirectly, they contribute to the shaping of the skeleton, maintenance of tone and elasticity of urogenital structures, changes in the epiphyses of the long bones that allow for the pubertal growth spurt and its termination, growth of axillary and pubic hair, and pigmentation of the nipples and genitals. Decline of estrogenic activity at the end of the menstrual cycle can bring on menstruation, although the cessation of progesterone secretion is the most important factor in the mature ovulatory cycle. However, in the preovulatory or nonovulatory cycle, estrogen is the primary determinant in the onset of menstruation. Estrogens also affect the release of pituitary gonadotropins. The pharmacologic effects of conjugated estrogens are similar to those of endogenous estrogens.

Oestrone Absorption

Well absorbed

Oestrone side effects and Toxicity

Nausea and vomiting

Oestrone Patient Information

Oestrone Organisms Affected

Humans and other mammals