Hormestrin
Brand names,
Hormestrin
Analogs
Hormestrin
Brand Names Mixture
- Cimicifuga Plex (Caulophyllum Thalictroides + Cimicifuga Racemosa + Copper + Cotton Plant + Estrone + Histamine Dihydrochloride + Hypothalamus + Magnesium Phosphate Dibasic + Pituitary Whole + Platinum + Sepia Officinalis L + Thyroid)
- Holis 98 (Dioscorea Vilosa + Estrone + Salvia + Saw Palmetto)
Hormestrin
Chemical_Formula
C18H22O2
Hormestrin
RX_link
No information avaliable
Hormestrin
fda sheet
Hormestrin
msds (material safety sheet)
Hormestrin
Synthesis Reference
G. Anner, K. Miescher, and Helv. Chem. Acta. 31, 2173(1948)
Hormestrin
Molecular Weight
270.366 g/mol
Hormestrin
Melting Point
254.5-256 oC
Hormestrin
H2O Solubility
3 g/100mL
Hormestrin
State
Solid
Hormestrin
LogP
4.067
Hormestrin
Dosage Forms
Vaginal cream; Vaginal suppository; Patch; Skin gel; Tablet; IM injectable suspension
Hormestrin
Indication
For management of Menopausal and postmenopausal disorders
Hormestrin
Pharmacology
Estrone, a synthetically prepared or naturally occurring steroidal estrogen obtained from pregnant equine urine, is the primary circulating estrogen after menopause. Estrone is naturally derived from the peripheral conversion of androstenedione by an aromatase enzyme found in adipose tissues and is converted to estradiol in peripheral tissues. Estropipate is piperazine-stabilized estrone sulfate. Estrone, and estropipate are used to treat abnormalities related to gonadotropin hormone dysfunction, vasomotor symptoms, atrophic vaginitis, and vulvar atrophy associated with menopause, and for the prevention of osteoporosis due to estrogen deficiency.
Hormestrin
Absorption
43%
Hormestrin
side effects and Toxicity
Symptoms of overdose include nausea and vomiting. Withdrawal bleeding may occur in females.
Hormestrin
Patient Information
Hormestrin
Organisms Affected
Humans and other mammals