Ketohydroxyestrin
Brand names,
Ketohydroxyestrin
Analogs
Ketohydroxyestrin
Brand Names Mixture
- Cimicifuga Plex (Caulophyllum Thalictroides + Cimicifuga Racemosa + Copper + Cotton Plant + Estrone + Histamine Dihydrochloride + Hypothalamus + Magnesium Phosphate Dibasic + Pituitary Whole + Platinum + Sepia Officinalis L + Thyroid)
- Holis 98 (Dioscorea Vilosa + Estrone + Salvia + Saw Palmetto)
Ketohydroxyestrin
Chemical_Formula
C18H22O2
Ketohydroxyestrin
RX_link
No information avaliable
Ketohydroxyestrin
fda sheet
Ketohydroxyestrin
msds (material safety sheet)
Ketohydroxyestrin
Synthesis Reference
G. Anner, K. Miescher, and Helv. Chem. Acta. 31, 2173(1948)
Ketohydroxyestrin
Molecular Weight
270.366 g/mol
Ketohydroxyestrin
Melting Point
254.5-256 oC
Ketohydroxyestrin
H2O Solubility
3 g/100mL
Ketohydroxyestrin
State
Solid
Ketohydroxyestrin
LogP
4.067
Ketohydroxyestrin
Dosage Forms
Vaginal cream; Vaginal suppository; Patch; Skin gel; Tablet; IM injectable suspension
Ketohydroxyestrin
Indication
For management of Menopausal and postmenopausal disorders
Ketohydroxyestrin
Pharmacology
Estrone, a synthetically prepared or naturally occurring steroidal estrogen obtained from pregnant equine urine, is the primary circulating estrogen after menopause. Estrone is naturally derived from the peripheral conversion of androstenedione by an aromatase enzyme found in adipose tissues and is converted to estradiol in peripheral tissues. Estropipate is piperazine-stabilized estrone sulfate. Estrone, and estropipate are used to treat abnormalities related to gonadotropin hormone dysfunction, vasomotor symptoms, atrophic vaginitis, and vulvar atrophy associated with menopause, and for the prevention of osteoporosis due to estrogen deficiency.
Ketohydroxyestrin
Absorption
43%
Ketohydroxyestrin
side effects and Toxicity
Symptoms of overdose include nausea and vomiting. Withdrawal bleeding may occur in females.
Ketohydroxyestrin
Patient Information
Ketohydroxyestrin
Organisms Affected
Humans and other mammals