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Todalgil Brand names, Todalgil Analogs

Todalgil Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Todalgil Chemical_Formula

C19H20N2O2

Todalgil RX_link

No information avaliable

Todalgil fda sheet

Todalgil msds (material safety sheet)

Todalgil MSDS

Todalgil Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Todalgil Molecular Weight

308.374 g/mol

Todalgil Melting Point

105 oC

Todalgil H2O Solubility

47.5 mg/L

Todalgil State

Solid

Todalgil LogP

4.214

Todalgil Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Todalgil Indication

For the treatment of backache and ankylosing spondylitis

Todalgil Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Todalgil Absorption

No information avaliable

Todalgil side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Todalgil Patient Information

No information avaliable

Todalgil Organisms Affected

Humans and other mammals