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Butatron Brand names, Butatron Analogs

Butatron Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Butatron Chemical_Formula

C19H20N2O2

Butatron RX_link

No information avaliable

Butatron fda sheet

Butatron msds (material safety sheet)

Butatron MSDS

Butatron Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Butatron Molecular Weight

308.374 g/mol

Butatron Melting Point

105 oC

Butatron H2O Solubility

47.5 mg/L

Butatron State

Solid

Butatron LogP

4.214

Butatron Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Butatron Indication

For the treatment of backache and ankylosing spondylitis

Butatron Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Butatron Absorption

No information avaliable

Butatron side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Butatron Patient Information

No information avaliable

Butatron Organisms Affected

Humans and other mammals