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Anerval Brand names, Anerval Analogs

Anerval Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Anerval Chemical_Formula

C19H20N2O2

Anerval RX_link

No information avaliable

Anerval fda sheet

Anerval msds (material safety sheet)

Anerval MSDS

Anerval Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Anerval Molecular Weight

308.374 g/mol

Anerval Melting Point

105 oC

Anerval H2O Solubility

47.5 mg/L

Anerval State

Solid

Anerval LogP

4.214

Anerval Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Anerval Indication

For the treatment of backache and ankylosing spondylitis

Anerval Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Anerval Absorption

No information avaliable

Anerval side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Anerval Patient Information

No information avaliable

Anerval Organisms Affected

Humans and other mammals