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Ticinil Brand names, Ticinil Analogs

Ticinil Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Ticinil Chemical_Formula

C19H20N2O2

Ticinil RX_link

No information avaliable

Ticinil fda sheet

Ticinil msds (material safety sheet)

Ticinil MSDS

Ticinil Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Ticinil Molecular Weight

308.374 g/mol

Ticinil Melting Point

105 oC

Ticinil H2O Solubility

47.5 mg/L

Ticinil State

Solid

Ticinil LogP

4.214

Ticinil Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Ticinil Indication

For the treatment of backache and ankylosing spondylitis

Ticinil Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Ticinil Absorption

No information avaliable

Ticinil side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Ticinil Patient Information

No information avaliable

Ticinil Organisms Affected

Humans and other mammals