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Alqoverin Brand names, Alqoverin Analogs

Alqoverin Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Alqoverin Chemical_Formula

C19H20N2O2

Alqoverin RX_link

No information avaliable

Alqoverin fda sheet

Alqoverin msds (material safety sheet)

Alqoverin MSDS

Alqoverin Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Alqoverin Molecular Weight

308.374 g/mol

Alqoverin Melting Point

105 oC

Alqoverin H2O Solubility

47.5 mg/L

Alqoverin State

Solid

Alqoverin LogP

4.214

Alqoverin Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Alqoverin Indication

For the treatment of backache and ankylosing spondylitis

Alqoverin Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Alqoverin Absorption

No information avaliable

Alqoverin side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Alqoverin Patient Information

No information avaliable

Alqoverin Organisms Affected

Humans and other mammals