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Fenilbutazona
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Fenilbutazona Brand names, Fenilbutazona Analogs

Fenilbutazona Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Fenilbutazona Chemical_Formula

C19H20N2O2

Fenilbutazona RX_link

No information avaliable

Fenilbutazona fda sheet

Fenilbutazona msds (material safety sheet)

Fenilbutazona MSDS

Fenilbutazona Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Fenilbutazona Molecular Weight

308.374 g/mol

Fenilbutazona Melting Point

105 oC

Fenilbutazona H2O Solubility

47.5 mg/L

Fenilbutazona State

Solid

Fenilbutazona LogP

4.214

Fenilbutazona Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Fenilbutazona Indication

For the treatment of backache and ankylosing spondylitis

Fenilbutazona Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Fenilbutazona Absorption

No information avaliable

Fenilbutazona side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Fenilbutazona Patient Information

No information avaliable

Fenilbutazona Organisms Affected

Humans and other mammals