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Buvetzone Brand names, Buvetzone Analogs

Buvetzone Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Buvetzone Chemical_Formula

C19H20N2O2

Buvetzone RX_link

No information avaliable

Buvetzone fda sheet

Buvetzone msds (material safety sheet)

Buvetzone MSDS

Buvetzone Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Buvetzone Molecular Weight

308.374 g/mol

Buvetzone Melting Point

105 oC

Buvetzone H2O Solubility

47.5 mg/L

Buvetzone State

Solid

Buvetzone LogP

4.214

Buvetzone Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Buvetzone Indication

For the treatment of backache and ankylosing spondylitis

Buvetzone Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Buvetzone Absorption

No information avaliable

Buvetzone side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Buvetzone Patient Information

No information avaliable

Buvetzone Organisms Affected

Humans and other mammals