Fenibutazona en es it fr

Fenibutazona Brand names, Fenibutazona Analogs

Fenibutazona Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Fenibutazona Chemical_Formula

C19H20N2O2

Fenibutazona RX_link

No information avaliable

Fenibutazona fda sheet

Fenibutazona msds (material safety sheet)

Fenibutazona MSDS

Fenibutazona Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Fenibutazona Molecular Weight

308.374 g/mol

Fenibutazona Melting Point

105 oC

Fenibutazona H2O Solubility

47.5 mg/L

Fenibutazona State

Solid

Fenibutazona LogP

4.214

Fenibutazona Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Fenibutazona Indication

For the treatment of backache and ankylosing spondylitis

Fenibutazona Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Fenibutazona Absorption

No information avaliable

Fenibutazona side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Fenibutazona Patient Information

No information avaliable

Fenibutazona Organisms Affected

Humans and other mammals