Nadozone en es it fr

Nadozone Brand names, Nadozone Analogs

Nadozone Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Nadozone Chemical_Formula

C19H20N2O2

Nadozone RX_link

No information avaliable

Nadozone fda sheet

Nadozone msds (material safety sheet)

Nadozone MSDS

Nadozone Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Nadozone Molecular Weight

308.374 g/mol

Nadozone Melting Point

105 oC

Nadozone H2O Solubility

47.5 mg/L

Nadozone State

Solid

Nadozone LogP

4.214

Nadozone Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Nadozone Indication

For the treatment of backache and ankylosing spondylitis

Nadozone Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Nadozone Absorption

No information avaliable

Nadozone side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Nadozone Patient Information

No information avaliable

Nadozone Organisms Affected

Humans and other mammals