Phebuzine
Phebuzine Brand names, Phebuzine Analogs
- 'Esteve'
- Alindor
- Alka Butazolidin
- Alkabutazona
- Alqoverin
- Ambene
- Anerval
- Anpuzone
- Antadol
- Anuspiramin
- Apo-Phenylbutazone
- Arthrizon
- Artizin
- Artrizin
- Artrizone
- Artropan
- Azdid
- Azobutyl
- Azolid
- B.T.Z.
- Benzone
- Betazed
- Bizolin
- Bizolin 200
- Bunetzone
- Busone
- Buta Phen
- Butacompren
- Butacote
- Butadion
- Butadiona
- Butadione
- Butagesic
- Butalan
- Butalgina
- Butalidon
- Butaluy
- Butapirazol
- Butapirazole
- Butapyrazole
- Butarecbon
- Butartril
- Butartrina
- Butatron
- Butazina
- Butazolidin
- Butazolidine
- Butazona
- Butazone
- Bute
- Butidiona
- Butiwas-Simple
- Butone
- Butoz
- Butylpyrin
- Buvetzone
- Buzon
- Chembutazone
- Cotylbutazone
- Digibutina
- Diossidone
- Diozol
- Diphebuzol
- Diphenylbutazone
- Ecobutazone
- Elmedal
- Equi Bute
- Equipalazone
- Eributazone
- Exrheudon N
- Febuzina
- Fenartil
- Fenibutal
- Fenibutasan
- Fenibutazona
- Fenibutol
- Fenilbutazona
- Fenilbutina
- Fenilbutine
- Fenilidina
- Fenotone
- Fenylbutazon
- Flexazone
- Ia-But
- Intalbut
- Intrabutazone
- Intrazone
- Ipsoflame
- Kadol
- Lingel
- Malgesic
- Mepha-Butazon
- Mephabutazon
- Mephabutazone
- Merizone
- Nadazone
- Nadozone
- Neo-Zoline
- Novophenyl
- PBZ
- Phebuzin
- Phebuzine
- Phenbutazol
- Phenbutazone
- Phenopyrine
- Phenyl-Mobuzon
- Phenylbutaz
- Phenylbutazonum
- Phenyzene
- Phenyzone
- Pirarreumol "B"
- Pirarreumol B
- Praecirheumin
- Pyrabutol
- Pyrazolidin
- Rectofasa
- Reudo
- Reudox
- Reumasyl
- Reumazin
- Reumazol
- Reumune
- Reumuzol
- Reupolar
- Robizon-V
- Robizone
- Robizone-V
- Rubatone
- Scanbutazone
- Schemergin
- Shigrodin
- Tazone
- Tencodyne
- Tetnor
- Tevcodyne
- Therazone
- Ticinil
- Todalgil
- Usaf Ge-15
- Uzone
- VAC-10
- Wescozone
- Zolaphen
- Zolidinum
- Zorane
Phebuzine Brand Names Mixture
- Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
- Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
- Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
Phebuzine Chemical_Formula
C19H20N2O2
Phebuzine RX_link
No information avaliable
Phebuzine fda sheet
Phebuzine msds (material safety sheet)
Phebuzine Synthesis Reference
Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)
Phebuzine Molecular Weight
308.374 g/mol
Phebuzine Melting Point
105 oC
Phebuzine H2O Solubility
47.5 mg/L
Phebuzine State
Solid
Phebuzine LogP
4.214
Phebuzine Dosage Forms
Bolus; Liquid; Paste; Powder; Solution; Tablet
Phebuzine Indication
For the treatment of backache and ankylosing spondylitis
Phebuzine Pharmacology
Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation
Phebuzine Absorption
No information avaliable
Phebuzine side effects and Toxicity
Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)
Phebuzine Patient Information
No information avaliable
Phebuzine Organisms Affected
Humans and other mammals
