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Azdid Brand names, Azdid Analogs

Azdid Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Azdid Chemical_Formula

C19H20N2O2

Azdid RX_link

No information avaliable

Azdid fda sheet

Azdid msds (material safety sheet)

Azdid MSDS

Azdid Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Azdid Molecular Weight

308.374 g/mol

Azdid Melting Point

105 oC

Azdid H2O Solubility

47.5 mg/L

Azdid State

Solid

Azdid LogP

4.214

Azdid Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Azdid Indication

For the treatment of backache and ankylosing spondylitis

Azdid Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Azdid Absorption

No information avaliable

Azdid side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Azdid Patient Information

No information avaliable

Azdid Organisms Affected

Humans and other mammals