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Reumuzol Brand names, Reumuzol Analogs

Reumuzol Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Reumuzol Chemical_Formula

C19H20N2O2

Reumuzol RX_link

No information avaliable

Reumuzol fda sheet

Reumuzol msds (material safety sheet)

Reumuzol MSDS

Reumuzol Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Reumuzol Molecular Weight

308.374 g/mol

Reumuzol Melting Point

105 oC

Reumuzol H2O Solubility

47.5 mg/L

Reumuzol State

Solid

Reumuzol LogP

4.214

Reumuzol Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Reumuzol Indication

For the treatment of backache and ankylosing spondylitis

Reumuzol Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Reumuzol Absorption

No information avaliable

Reumuzol side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Reumuzol Patient Information

No information avaliable

Reumuzol Organisms Affected

Humans and other mammals