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Butylpyrin Brand names, Butylpyrin Analogs

Butylpyrin Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Butylpyrin Chemical_Formula

C19H20N2O2

Butylpyrin RX_link

No information avaliable

Butylpyrin fda sheet

Butylpyrin msds (material safety sheet)

Butylpyrin MSDS

Butylpyrin Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Butylpyrin Molecular Weight

308.374 g/mol

Butylpyrin Melting Point

105 oC

Butylpyrin H2O Solubility

47.5 mg/L

Butylpyrin State

Solid

Butylpyrin LogP

4.214

Butylpyrin Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Butylpyrin Indication

For the treatment of backache and ankylosing spondylitis

Butylpyrin Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Butylpyrin Absorption

No information avaliable

Butylpyrin side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Butylpyrin Patient Information

No information avaliable

Butylpyrin Organisms Affected

Humans and other mammals