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Reumune Brand names, Reumune Analogs

Reumune Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Reumune Chemical_Formula

C19H20N2O2

Reumune RX_link

No information avaliable

Reumune fda sheet

Reumune msds (material safety sheet)

Reumune MSDS

Reumune Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Reumune Molecular Weight

308.374 g/mol

Reumune Melting Point

105 oC

Reumune H2O Solubility

47.5 mg/L

Reumune State

Solid

Reumune LogP

4.214

Reumune Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Reumune Indication

For the treatment of backache and ankylosing spondylitis

Reumune Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Reumune Absorption

No information avaliable

Reumune side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Reumune Patient Information

No information avaliable

Reumune Organisms Affected

Humans and other mammals