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Butapirazol Brand names, Butapirazol Analogs

Butapirazol Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Butapirazol Chemical_Formula

C19H20N2O2

Butapirazol RX_link

No information avaliable

Butapirazol fda sheet

Butapirazol msds (material safety sheet)

Butapirazol MSDS

Butapirazol Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Butapirazol Molecular Weight

308.374 g/mol

Butapirazol Melting Point

105 oC

Butapirazol H2O Solubility

47.5 mg/L

Butapirazol State

Solid

Butapirazol LogP

4.214

Butapirazol Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Butapirazol Indication

For the treatment of backache and ankylosing spondylitis

Butapirazol Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Butapirazol Absorption

No information avaliable

Butapirazol side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Butapirazol Patient Information

No information avaliable

Butapirazol Organisms Affected

Humans and other mammals