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Buzon Brand names, Buzon Analogs

Buzon Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Buzon Chemical_Formula

C19H20N2O2

Buzon RX_link

No information avaliable

Buzon fda sheet

Buzon msds (material safety sheet)

Buzon MSDS

Buzon Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Buzon Molecular Weight

308.374 g/mol

Buzon Melting Point

105 oC

Buzon H2O Solubility

47.5 mg/L

Buzon State

Solid

Buzon LogP

4.214

Buzon Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Buzon Indication

For the treatment of backache and ankylosing spondylitis

Buzon Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Buzon Absorption

No information avaliable

Buzon side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Buzon Patient Information

No information avaliable

Buzon Organisms Affected

Humans and other mammals