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Butartril Brand names, Butartril Analogs

Butartril Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Butartril Chemical_Formula

C19H20N2O2

Butartril RX_link

No information avaliable

Butartril fda sheet

Butartril msds (material safety sheet)

Butartril MSDS

Butartril Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Butartril Molecular Weight

308.374 g/mol

Butartril Melting Point

105 oC

Butartril H2O Solubility

47.5 mg/L

Butartril State

Solid

Butartril LogP

4.214

Butartril Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Butartril Indication

For the treatment of backache and ankylosing spondylitis

Butartril Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Butartril Absorption

No information avaliable

Butartril side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Butartril Patient Information

No information avaliable

Butartril Organisms Affected

Humans and other mammals