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Butapirazole Brand names, Butapirazole Analogs

Butapirazole Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Butapirazole Chemical_Formula

C19H20N2O2

Butapirazole RX_link

No information avaliable

Butapirazole fda sheet

Butapirazole msds (material safety sheet)

Butapirazole MSDS

Butapirazole Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Butapirazole Molecular Weight

308.374 g/mol

Butapirazole Melting Point

105 oC

Butapirazole H2O Solubility

47.5 mg/L

Butapirazole State

Solid

Butapirazole LogP

4.214

Butapirazole Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Butapirazole Indication

For the treatment of backache and ankylosing spondylitis

Butapirazole Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Butapirazole Absorption

No information avaliable

Butapirazole side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Butapirazole Patient Information

No information avaliable

Butapirazole Organisms Affected

Humans and other mammals