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Fenibutol Brand names, Fenibutol Analogs

Fenibutol Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Fenibutol Chemical_Formula

C19H20N2O2

Fenibutol RX_link

No information avaliable

Fenibutol fda sheet

Fenibutol msds (material safety sheet)

Fenibutol MSDS

Fenibutol Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Fenibutol Molecular Weight

308.374 g/mol

Fenibutol Melting Point

105 oC

Fenibutol H2O Solubility

47.5 mg/L

Fenibutol State

Solid

Fenibutol LogP

4.214

Fenibutol Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Fenibutol Indication

For the treatment of backache and ankylosing spondylitis

Fenibutol Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Fenibutol Absorption

No information avaliable

Fenibutol side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Fenibutol Patient Information

No information avaliable

Fenibutol Organisms Affected

Humans and other mammals