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Fenilidina Brand names, Fenilidina Analogs

Fenilidina Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Fenilidina Chemical_Formula

C19H20N2O2

Fenilidina RX_link

No information avaliable

Fenilidina fda sheet

Fenilidina msds (material safety sheet)

Fenilidina MSDS

Fenilidina Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Fenilidina Molecular Weight

308.374 g/mol

Fenilidina Melting Point

105 oC

Fenilidina H2O Solubility

47.5 mg/L

Fenilidina State

Solid

Fenilidina LogP

4.214

Fenilidina Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Fenilidina Indication

For the treatment of backache and ankylosing spondylitis

Fenilidina Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Fenilidina Absorption

No information avaliable

Fenilidina side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Fenilidina Patient Information

No information avaliable

Fenilidina Organisms Affected

Humans and other mammals