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Azolid Brand names, Azolid Analogs

Azolid Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Azolid Chemical_Formula

C19H20N2O2

Azolid RX_link

No information avaliable

Azolid fda sheet

Azolid msds (material safety sheet)

Azolid MSDS

Azolid Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Azolid Molecular Weight

308.374 g/mol

Azolid Melting Point

105 oC

Azolid H2O Solubility

47.5 mg/L

Azolid State

Solid

Azolid LogP

4.214

Azolid Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Azolid Indication

For the treatment of backache and ankylosing spondylitis

Azolid Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Azolid Absorption

No information avaliable

Azolid side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Azolid Patient Information

No information avaliable

Azolid Organisms Affected

Humans and other mammals