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Tencodyne Brand names, Tencodyne Analogs

Tencodyne Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Tencodyne Chemical_Formula

C19H20N2O2

Tencodyne RX_link

No information avaliable

Tencodyne fda sheet

Tencodyne msds (material safety sheet)

Tencodyne MSDS

Tencodyne Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Tencodyne Molecular Weight

308.374 g/mol

Tencodyne Melting Point

105 oC

Tencodyne H2O Solubility

47.5 mg/L

Tencodyne State

Solid

Tencodyne LogP

4.214

Tencodyne Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Tencodyne Indication

For the treatment of backache and ankylosing spondylitis

Tencodyne Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Tencodyne Absorption

No information avaliable

Tencodyne side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Tencodyne Patient Information

No information avaliable

Tencodyne Organisms Affected

Humans and other mammals