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Equi Bute Brand names, Equi Bute Analogs

Equi Bute Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Equi Bute Chemical_Formula

C19H20N2O2

Equi Bute RX_link

No information avaliable

Equi Bute fda sheet

Equi Bute msds (material safety sheet)

Equi_Bute MSDS

Equi Bute Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Equi Bute Molecular Weight

308.374 g/mol

Equi Bute Melting Point

105 oC

Equi Bute H2O Solubility

47.5 mg/L

Equi Bute State

Solid

Equi Bute LogP

4.214

Equi Bute Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Equi Bute Indication

For the treatment of backache and ankylosing spondylitis

Equi Bute Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Equi Bute Absorption

No information avaliable

Equi Bute side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Equi Bute Patient Information

No information avaliable

Equi Bute Organisms Affected

Humans and other mammals