Reumazol en es it fr

Reumazol Brand names, Reumazol Analogs

Reumazol Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Reumazol Chemical_Formula

C19H20N2O2

Reumazol RX_link

No information avaliable

Reumazol fda sheet

Reumazol msds (material safety sheet)

Reumazol MSDS

Reumazol Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Reumazol Molecular Weight

308.374 g/mol

Reumazol Melting Point

105 oC

Reumazol H2O Solubility

47.5 mg/L

Reumazol State

Solid

Reumazol LogP

4.214

Reumazol Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Reumazol Indication

For the treatment of backache and ankylosing spondylitis

Reumazol Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Reumazol Absorption

No information avaliable

Reumazol side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Reumazol Patient Information

No information avaliable

Reumazol Organisms Affected

Humans and other mammals