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Butazina Brand names, Butazina Analogs

Butazina Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Butazina Chemical_Formula

C19H20N2O2

Butazina RX_link

No information avaliable

Butazina fda sheet

Butazina msds (material safety sheet)

Butazina MSDS

Butazina Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Butazina Molecular Weight

308.374 g/mol

Butazina Melting Point

105 oC

Butazina H2O Solubility

47.5 mg/L

Butazina State

Solid

Butazina LogP

4.214

Butazina Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Butazina Indication

For the treatment of backache and ankylosing spondylitis

Butazina Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Butazina Absorption

No information avaliable

Butazina side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Butazina Patient Information

No information avaliable

Butazina Organisms Affected

Humans and other mammals