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Artropan Brand names, Artropan Analogs

Artropan Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Artropan Chemical_Formula

C19H20N2O2

Artropan RX_link

No information avaliable

Artropan fda sheet

Artropan msds (material safety sheet)

Artropan MSDS

Artropan Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Artropan Molecular Weight

308.374 g/mol

Artropan Melting Point

105 oC

Artropan H2O Solubility

47.5 mg/L

Artropan State

Solid

Artropan LogP

4.214

Artropan Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Artropan Indication

For the treatment of backache and ankylosing spondylitis

Artropan Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Artropan Absorption

No information avaliable

Artropan side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Artropan Patient Information

No information avaliable

Artropan Organisms Affected

Humans and other mammals