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Butacompren Brand names, Butacompren Analogs

Butacompren Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Butacompren Chemical_Formula

C19H20N2O2

Butacompren RX_link

No information avaliable

Butacompren fda sheet

Butacompren msds (material safety sheet)

Butacompren MSDS

Butacompren Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Butacompren Molecular Weight

308.374 g/mol

Butacompren Melting Point

105 oC

Butacompren H2O Solubility

47.5 mg/L

Butacompren State

Solid

Butacompren LogP

4.214

Butacompren Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Butacompren Indication

For the treatment of backache and ankylosing spondylitis

Butacompren Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Butacompren Absorption

No information avaliable

Butacompren side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Butacompren Patient Information

No information avaliable

Butacompren Organisms Affected

Humans and other mammals