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Reumasyl Brand names, Reumasyl Analogs

Reumasyl Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Reumasyl Chemical_Formula

C19H20N2O2

Reumasyl RX_link

No information avaliable

Reumasyl fda sheet

Reumasyl msds (material safety sheet)

Reumasyl MSDS

Reumasyl Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Reumasyl Molecular Weight

308.374 g/mol

Reumasyl Melting Point

105 oC

Reumasyl H2O Solubility

47.5 mg/L

Reumasyl State

Solid

Reumasyl LogP

4.214

Reumasyl Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Reumasyl Indication

For the treatment of backache and ankylosing spondylitis

Reumasyl Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Reumasyl Absorption

No information avaliable

Reumasyl side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Reumasyl Patient Information

No information avaliable

Reumasyl Organisms Affected

Humans and other mammals