PharmacyCodes



Bizolin en es it fr

Bizolin Brand names, Bizolin Analogs

Bizolin Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Bizolin Chemical_Formula

C19H20N2O2

Bizolin RX_link

No information avaliable

Bizolin fda sheet

Bizolin msds (material safety sheet)

Bizolin MSDS

Bizolin Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Bizolin Molecular Weight

308.374 g/mol

Bizolin Melting Point

105 oC

Bizolin H2O Solubility

47.5 mg/L

Bizolin State

Solid

Bizolin LogP

4.214

Bizolin Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Bizolin Indication

For the treatment of backache and ankylosing spondylitis

Bizolin Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Bizolin Absorption

No information avaliable

Bizolin side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Bizolin Patient Information

No information avaliable

Bizolin Organisms Affected

Humans and other mammals