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Reupolar Brand names, Reupolar Analogs

Reupolar Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Reupolar Chemical_Formula

C19H20N2O2

Reupolar RX_link

No information avaliable

Reupolar fda sheet

Reupolar msds (material safety sheet)

Reupolar MSDS

Reupolar Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Reupolar Molecular Weight

308.374 g/mol

Reupolar Melting Point

105 oC

Reupolar H2O Solubility

47.5 mg/L

Reupolar State

Solid

Reupolar LogP

4.214

Reupolar Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Reupolar Indication

For the treatment of backache and ankylosing spondylitis

Reupolar Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Reupolar Absorption

No information avaliable

Reupolar side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Reupolar Patient Information

No information avaliable

Reupolar Organisms Affected

Humans and other mammals